A recent study published in PLOS Medicine highlights how common combinations of food additives used in ultraprocessed foods could pose greater health risks when consumed together, rather than individually. These chemical clusters—often found in packaged snacks, diet sodas, processed meats, and ready-to-eat meals—may significantly contribute to the growing diabetes epidemic.
What Are Ultraprocessed Foods?
Ultraprocessed foods (UPFs) are industrially manufactured products that go through multiple processing steps and contain additives not typically used in home cooking. These include:
- Artificial sweeteners
- Flavor enhancers
- Coloring agents
- Emulsifiers and preservatives
- Modified starches and stabilizers
Examples include soda, flavored yogurts, processed breads, chips, and fast food items. According to the NOVA food classification system, ultraprocessed foods differ from minimally processed items like fresh fruits, vegetables, or simple canned goods by their high additive content and industrial origin.
Key Findings: Additives May Be More Dangerous in Combination
Researchers from the French NutriNet-Santé study—an ongoing project involving over 108,000 adults—analyzed participants' long-term dietary habits. Using detailed ingredient data from the Open Food Facts database, they identified frequent additive combinations and their correlation with type 2 diabetes over time.
Two major additive clusters were linked to a statistically significant increase in type 2 diabetes risk:
Cluster 1:
Includes modified starches, guar gum, xanthan gum, pectin, carrageenan, polyphosphates, potassium sorbates, and curcumin—often found in:
- Creamy dairy desserts (e.g., puddings)
- Cheese dips
- Commercial broths
Cluster 2:
Includes citric acid, phosphoric acid, acesulfame potassium (Ace-K), aspartame, sucralose, Arabic gum, and carnauba wax—commonly used in:
- Diet sodas
- Sugar-free beverages
- Candy and flavored drinks
These findings suggest that chronic exposure to combinations of sweeteners and emulsifiers can disrupt gut health, increase inflammation, and impair insulin regulation—key contributors to diabetes.
Why This Matters: Additive Regulation Under Scrutiny
Current food safety regulations typically assess additives in isolation, ignoring their synergistic effects when consumed as part of ultraprocessed food clusters. Experts like Dr. Carlos Monteiro, creator of the NOVA classification, argue this is a major oversight.
“Additives are consumed in clusters, not individually,” Monteiro said. “This study validates concerns about their cumulative health effects.”
Industry Pushback
Despite the findings, industry groups like the International Council of Beverages Associations (ICBA) called the study “absurd,” stating that additives are “backed by decades of robust scientific evidence.” However, researchers stress that their data is the first to evaluate real-world exposure to additive combinations at this scale.
Health Impact of Ultraprocessed Foods Beyond Diabetes
Ultraprocessed foods have been previously linked to:
- Obesity
- Heart disease
- Cognitive decline
- Cancer
A 2023 study even found that consuming just a few ultraprocessed items in a healthy diet raised the risk of stroke and memory problems.
What Can You Do? Tips to Reduce Ultraprocessed Food Intake
To protect your health and reduce your risk of diabetes:
- Choose whole, natural foods like fruits, vegetables, legumes, and whole grains.
- Cook meals at home using simple ingredients.
- Read nutrition labels and avoid products with long ingredient lists or unfamiliar additives.
- Limit sugary beverages and processed snacks.
Conclusion: The Hidden Dangers of Food Additive Clusters
This landmark study sheds light on a previously overlooked factor in diabetes risk: not just the presence of food additives, but how they interact when consumed together. With ultraprocessed foods dominating modern diets, it's time for public health policy to catch up and consider the real-world impact of these chemical combinations.
Sources: CNN +Sites
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